Cincinnati Children’s international collaborative to fund three pediatric medical device projects

A recently launched partnership between Cincinnati Children’s Hospital Medical Center and Ben-Gurion University in Israel is funding the research and development of three pediatric-specific medical devices.

The collaboration, which pairs the medical expertise of CCHMC physicians with the technical and engineering capabilities of BGU, started with nearly 80 unaddressed problems facing surgeons and physicians. After reviewing these ideas and proposed solutions, 10 projects underwent rigorous application cycles, thorough market analyses and review by internal and external stakeholders.

The initial three projects that will be funded—a smart sensing catheter, a surfactant-delivery device, and an image-guided needle insertion device—have potential to not only improve patient care and outcomes, but also reduce costs to the healthcare system.

“The pediatric market, especially with regard to medical devices, has historically been neglected primarily due to prohibitive development costs,” said Niki Robinson, assistant vice president of CCHMC’s Center for Technology Commercialization. “This initiative presents an unprecedented opportunity for early stage ideas to receive funding and move through a development plan backed by world-class physicians and engineers.”

The smart sensing catheter concept was developed by Richard Azizkhan, MD, surgeon-in-chief at CCHMC and the Lester W. Martin Chair of Pediatric Surgery, and Ibrahim Abdulhalim, professor of electro-optical engineering at BGU. The device provides immediate and continuous assessment of the metabolic and physiological profile of critically ill infants and small children. “Secondarily, this technology will reduce the need for repeated tests, thus reducing costs for the health system and society,” said Azizkhan.

The surfactant delivery device concept was developed by Jeffrey Whitsett, MD, co-director, Perinatal Institute and chief, section of neonatology, perinatal and pulmonary biology at CCHMC, and Joseph Kost, dean of the faculty of engineering sciences and professor of biomedical engineering at BGU. It consists of a delivery system for prolonged administration of surfactants to the lungs of premature babies using nanoparticles. Current procedures do not allow for the sustained release of proteins or other complex particles in the alveoli of infants or adults.

Daniel von Allmen, MD, director, Division of General and Thoracic Surgery at CCHMC, and Hugo Guterman, professor of electrical and computer engineering at BGU are collaborating on the image guided needle insertion device concept. It combines sophisticated new imaging techniques with the precision of robotics to improve the accuracy of many procedures.

Each project will receive up to $100,000 in the first round, with all funding contingent upon achieving project-specific developmental milestones.

Speaking to the value of early stage investment in research, von Allmen said, “One of the enormous struggles for physicians, many of whom are very experienced in their fields and knowledgeable about challenges to care, is the ability to get an idea from the back of a napkin in the cafeteria to a coordinated development effort. Cincinnati Children’s has put a lot of resources into creating the infrastructure to make the translation of good ideas to products a reality.”

Cincinnati-based seed-stage investor CincyTech and Israel-based Ridgeback Business Development helped evaluate the projects.

Recent Posts

Blog Post Archive

Blog Post Categories

Search the Blog

Newsticker


BioOhio Member Mark BioOhio Member

Interview with Cedarville University School of Pharmacy Dean Marc Sweeney | Pharmacy Times, December 19, 2014

Fathom Healthcare to embrace growth, digital health intervention in 2015 | PR Newswire, December 19, 2014

Cleveland Clinic spins out 71st company, Centerline Biomedical’s 3D surgical platform to reduce radiation exposure during operations | MedCity News, December 18, 2014

Northeast Ohio Medical University (NEOMED) and Mercy Health team up on scholarship program | IndeOnline, December 17, 2014

New distribution partnership between Ganeden Biotech and Grupo Saporiti will increase availability of GanedenBC30 in South America | Ganeden Biotech, December 17, 2014

Sparton acquires Industrial Electronic Devices, makers of ruggedized displays for electronics | Business Wire, December 17, 2014

Columbus downtown building where cancer drugs were once made might be demolished | The Columbus Dispatch, December 17, 2014

Health and Human Services awards Ohio $75 million to implement and test health care payment and service delivery models, improve care, lower costs | Ohio Hospital Association, December 16, 2014

Tedia chairman Elinora Park honored by the Cincinnati Regional Chamber of Commerce | PR Web, December 16, 2014

Cleveland HeartLab is the fastest growing private health care company in the Cleveland metro area according to Inc. | Inc., December 16, 2014

US Endoscopy announces distribution agreement for the EndoRings device | US Endoscopy, December 16, 2014

CincyTech portfolio companies raising $200 million in investor capital by end of 2014 | Cincinnati.com, December 16, 2014

Data presented by independent academic collaborators demonstrate ability of novel Manocept Immunotherapy to kill activated macrophages from KS patients, Macrophage Therapeutics, Navidea Biopharmaceuticals | Business Wire, December 15, 2014

Clinical Research Management (ClinicalRM) announces clinical trial evaluating effectiveness of convalescent plasma therapy for the treatment of Ebola underway in Liberia | PR Newswire, December 15, 2014

Alkermes announces initiation of clinical study of extended durations of Aripiprazole Lauroxil for treatment of schizophrenia | Business Wire, December 15, 2014

Ohio Northern University receives $1.21 million grant to instill the entrepreneurial mindset in engineering undergraduates | PR Newswire, December 15, 2014

Nationwide Children’s and OhioHealth planning campus in Delaware County | Columbus Business First, December 15, 2014

Akron couple donates $2 million for cancer research and education at Summa Health System | Akron Beacon Journal, December 13, 2014

Battelle, The Ohio State University and the Ohio Soybean Council developing improved soybean meal for aquaculture | The Fish Site, December 12, 2014

Wright-Patterson AFB Air Force Research Laboratory to hire 325 scientists and engineers in the next year | Dayton Daily News, December 12, 2014