Nationwide Children’s Hospital study identifies potential new pathway for drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children’s Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that is crucial to new drug development. The study appears in PLOS ONE.

More than one-third of drugs on the market work by targeting G protein-coupled receptors that control how cells communicate and function. With many hundreds of members, G protein-coupled receptors are the largest family of signaling receptors throughout the body. Full press release here.

Recent Posts

Blog Post Archive

Blog Post Categories

Search the Blog

Newsticker


BioOhio Member Mark BioOhio Member

CTI Clinical Trial & Consulting Services continues to grow with promotions and new hires | Cincinnati.com, April 22, 2014

Austen BioInnovation Institute in Akron presenting two FDA events in one day, April 29 | Austen BioInnovation Institute in Akron, April 22, 2014

OSU collaboration with California’s Oakbio awarded $500k from Canada’s CCEMC to develop biofuels | PR Newswire, April 22, 2014

OSU students’ non-polluting KAir battery wins $100K from US DOE | Columbus Business First, April 22, 2014

The Medical Imaging Technology Partnering Forum part of Cleveland’s medical imaging strength | Cleveland.com, April 22, 2014

Akebia Therapeutics stock rose 55% last week, from below $17 to above $26 | Cincinnati Business Courier, April 21, 2014

The Austen BioInnovation Institute in Akron working with Nottingham Spirk, a Cleveland-based design firm | Akron Beacon Journal, April 21, 2014

CincyTech discusses recent funding for Assurex Health & Sirrus (Bioformix) | Cincinnati Business Courier, April 21, 2014

Akron Children’s joins with Cincinnati Children’s to offer access to new cancer treatments | Akron Beacon Journal, April 20, 2014

OSU Biomedical Engineering students and OncoFilter partners Kinshuk Mitra and Brett Geiger featured on 10TV Columbus | WBNS 10TV Columbus, April 19, 2014

Case Western Reserve University event emphasizes a constellation of research (slideshow) | Cleveland.com, April 19, 2014

Airway Therapeutics granted orphan designation for its product to prevent BPD by European regulatory authority | Cincinnati.com, April 19, 2014

Assurex Health and Sirrus (Bioformix) lead 2014 Q1 funding rounds | Cincinnati.com, April 18, 2014

PhRMA Annual Meeting keynote speakers available on YouTube | PhRMA, April 18, 2014

Alkermes CEO Richard Pops speaks with Xconomy about building the business | Xconomy.com, April 18, 2014

Case Western Reserve University scientists discuss a portable malaria detector (video) | Inside Science TV, April 18, 2014

Ashland University Schar Nursing College starts Doctor of Nursing Program | WMFD Mansfield, April 18, 2014

Kent State Researchers discover new liquid crystal structure | Kent State University, April 17, 2014

ChanTest Webinar on the CiPA Initiative, defining a new paradigm in the field of cardiac safety (pdf) | ChanTest, April 17, 2014

Ethicon develops the suture of the future at €80 million Limerick, Ireland plant | Limerick Leader, April 16, 2014