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July COVID-19 Inventor Showcase: Enhancing Innate COVID-19 Immunity
July 14 @ 12:00 pm - 1:00 pm
The Optimizing Innovation, Commercialization and Entrepreneurship of Biomedical Research program of the CCTS, in partnership with the Corporate Engagement Office and Nationwide Children’s Hospital’s Office of Technology Commercialization, is launching a new Panel Speaker Series in response to the urgent need for academic innovations to combat the global pandemic. This series will feature some of the work happening on our campuses at an unprecedented pace on the front lines of innovation.
The race to find a cure for COVID-19 began on January 10, 2020, when the Chinese government released the genetic sequence of the virus – SARS-CoV-2 – responsible for the global pandemic of an extremely spreadable and potentially fatal disease. Researchers around the world began to build bits of the virus in their labs to develop therapies, with the aim of making us immune. Now, after 500,000 deaths, WHO warns worst of coronavirus pandemic is “yet to come”. Although most of the COVID-19 patients have mild or moderate courses, up to 5%–10% can have severe, potentially life-threatening course – hence, the urgent need for effective drugs. Join us to learn how researchers at Nationwide Children’s Hospital developed a method for generating large numbers of clinical-grade Natural Killer (NK) cells for cancer therapy which has the potential to augment the innate immunity of high-risk patients with mild or moderate COVID-19 disease and to prevent progression to severe COVID-19 disease.
July COVID-19 Inventor Team
• Chris P. Ouellette, MD, Section of Infectious Diseases and Host Defense Program at Nationwide Children’s Hospital and Assistant professor of Pediatrics at The Ohio State University College of Medicine.
• Dean Anthony Lee, MD, PhD, Division of Hematology and Oncology at Nationwide Children’s Hospital and Professor of Pediatrics at The Ohio State University College of Medicine and the DiMarco Family Endowed Chair in Cell-Based Therapy.
July Innovation Resource Team
- Nationwide Children’s Hospital Drug and Device Development Services: Kevin Bosse, Ph.D., RAC
- Nationwide Children’s Hospital Host Defense Program: Christopher P. Ouellette, MD
- Nationwide Children’s Hospital Cellular Therapy and Cancer Immunology Program: Margaret Lamb, MD
- OSU/NCH Campus GMP Facilities for Cell Therapy Manufacturing: Dean Lee, MD, PhD