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New cancer drug candidate from Cincinnati Children’s shows early promise

Researchers from Cincinnati Children’s Hospital Medical Center have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of developing neurons. The research finding are published in this week’s online issue of Chemistry & Biology. The scientists named their lead drug candidate “Rhosin” and […]

June 22, 2012

Nationwide Children’s researchers develop drug to target cancerous bone tumor in children

Dr. Jiayuh Lin and colleagues at Nationwide Children’s Hospital have developed a drug to target the most common cancerous bone tumor in children, osteosarcoma, using a version of the FDA-approved drug, Celebrex. With the help of a two-year, $200,000 grant from Alex’s Lemonade Stand Foundation for Childhood Cancer, the team will begin testing the drug […]

June 21, 2012

Ohio among top states in bioscience employment gains over past decade

Released today at the 2012 BIO International Convention, a new Battelle/BIO State Bioscience Industry Development report signals significant job growth in the bioscience sector over the past decade, indicating the importance of the biosciences as an economic driver for the nation. [The bioscience industry] has fared much better than the overall economy through the recent […]

June 19, 2012

A biomedical morning at the Statehouse

BioOhio made the Ohio Statehouse home this morning. President & CEO Tony Dennis joined Dr. Michael Caligiuri, CEO of the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, and other officials to talk about the significant economic impact of pharmaceutical clinical trials conducted in Ohio. The We Work for Health press conference […]

June 13, 2012

‘Exciting times’ for Ohio diagnostics company

Hubbard, Ohio-based NanoLogix is collaborating with University of Texas Health Science Center on a multi-well, microplate reader variant of the company’s BioNanoFilter (BNF) diagnostics for use in large volume laboratory environments. Early analysis of the multi-well plates shows exceptionally fast live-threat results similar to the company’s standard BNF technology. The technology will be shown off […]

June 12, 2012

Medical device tax repeal bill approved by House

The U.S. House of Representatives voted 270-146 yesterday to pass a bill repealing a planned 2.3 percent excise tax on medical device sales. See articles on this everywhere, but here’s one from Bloomberg. And here’s AdvaMed’s official response.

June 8, 2012

‘When NIH catches a cold, Ohio research catches pneumonia’

That’s from a Cleveland Plain Dealer article quoting Ohio State University College of Medicine Dean Charles J. Lockwood. Yesterday, representatives of Ohio medical schools met with NIH Francis S. Collins and eight Ohio members of Congress to discuss directing more rsearch funding to the state’s biomedical sector. When NIH research dollars are tight, Lockwood said […]

June 7, 2012

Battelle unveils drug discovery collaboration model

Dubbed CoLab, the Battelle Drug Discovery CoLaborative aims to bring together a variety of industry-leading companies to deliver the highest quality of mid- to late-stage drug discovery services through a single, integrated approach. The overall goal is to de-risk drug candidates earlier in the discovery phase, which could potentially save significant time and money for […]

June 6, 2012

OSU researchers find “life-and-death” molecule on chronic leukemia cells

A new study has identified a life-and-death signaling role for a molecule on the surface of immune cells involved in chronic leukemia. The finding could lead to more effective therapy for chronic lymphocytic leukemia (CLL), an as yet incurable cancer that occurs in more than 16,000 Americans annually. Led by researchers at the Ohio State […]

June 5, 2012

Harrington Discovery Institutes’ grant program aims to accelerate drug discovery and development

Earlier this month, University Hospitals Case Medical Center’s Harrington Discovery Institute announced a grant competition that serves as a nationwide search for physician-scientists seeking support to accelerate their promising drug discoveries into novel treatments for patients. The Harrington Scholar-Innovator grants will create a new funding pathway for these researchers.

May 31, 2012